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Updated 1 week ago · Independent Analysis
Cisco Secure Endpoint vs SentinelOne
Capability Overview
Cisco Secure Endpointvs SentinelOne
4.5G2-0.4 vs SentinelOne
Only in Cisco Secure Endpoint
- ✦ Next-Gen Antivirus
- ✦ Device Trajectory
- ✦ Orbital Advanced Search
From $6.75/moFortune 500 users · est. 1984
SentinelOnevs Cisco Secure Endpoint
4.9G2+0.4 vs Cisco Secure Endpoint
Only in SentinelOne
- ✦ AI-Powered Endpoint Protection
- ✦ XDR (Extended Detection)
- ✦ Autonomous Response (Storyline)
14k+ users · est. 2013
Quick VerdictIndependent Analysis
Cisco Secure Endpoint and SentinelOne are both Endpoint Security (XDR/EDR) tools. Compare features, pricing, and ratings below to find the best fit for your team.
When to Choose Cisco Secure Endpoint vs SentinelOne
The question that matters: “In what situation will I regret choosing A over B after 3 months?”
Scenario: XDR Correlation Across Cisco and
Cisco Secure Endpoint
XDR Correlation Across Cisco and Third-Party Telemetry
Cisco XDR ingests data from Secure Endpoint, Firewall, and third-party SIEM sources, correlating events into incident stories with MITRE ATT&CK mapping and suggested response actions.
SentinelOne
Full Attack Story Reconstruction From Endpoint Telemetry
Storyline stitches every process, file, and network event into a causal chain, giving analysts a complete attack narrative in under 60 seconds instead of manually correlating dozens of log events.
Cisco Secure Endpoint Unique Strength
Zero Trust Network Access via Cisco Duo MFA
Cisco Duo enforces MFA and device trust checks before every application access, blocking 99.9% of account compromise attempts on applications that previously relied on password-only authentication.
→ Choose Cisco Secure Endpoint if this scenario applies to you. SentinelOne doesn't offer a comparable solution.
Cisco Secure Endpoint Unique Strength
Umbrella DNS Filtering for Remote Workers Without VPN
Cisco Umbrella blocks malicious domains at the DNS layer for off-network devices, providing threat protection to remote workers without routing all traffic through a central VPN gateway.
→ Choose Cisco Secure Endpoint if this scenario applies to you. SentinelOne doesn't offer a comparable solution.
SentinelOne Unique Strength
Autonomous Ransomware Rollback in Under 5 Minutes
SentinelOne's Storyline Active Response kills malicious processes, quarantines files, and rolls back ransomware-encrypted files autonomously, reducing mean time to remediate from 4 hours to under 5 minutes.
→ Choose SentinelOne if this scenario applies to you. Cisco Secure Endpoint doesn't offer a comparable solution.
SentinelOne Unique Strength
Deep Visibility Threat Hunting Across 14 Days of EDR Data
SentinelOne's Deep Visibility lets hunters query 14 days of endpoint telemetry using a SQL-like syntax, finding indicators of compromise across thousands of endpoints in minutes.
→ Choose SentinelOne if this scenario applies to you. Cisco Secure Endpoint doesn't offer a comparable solution.
Pricing Comparison & PlansHigh· Verified May 30, 2026
Cisco Secure Endpoint Plans
Paid plans only
Secure Endpoint Essentials
$6.75/user/moBest for: This plan provides essential endpoint protection, ideal for small to medium businesses needing core security features without advanced customization.
- ✓malware detection
- ✓web filtering
- ✓real-time monitoring
- ✓threat detection
View on vendor site
MOST POPULARSecure Endpoint Advantage
Contact SalesBest for: Contact sales for custom pricing
- ✓XDR capabilities
- ✓endpoint investigations
- ✓incident management
- ✓threat intelligence
- ✓vulnerability management
View on vendor site
Secure Endpoint Premier
Contact SalesBest for: Contact sales for custom pricing
- ✓ThreatX hunting
- ✓centralized management
- ✓behavioral analytics
- ✓machine learning
- ✓retrospective analysis
View on vendor site
SentinelOne Plans
Paid plans only
Enterprise
Contact SalesBest for: The Enterprise plan provides the most advanced security and management options for complex environments
- ✓All capabilities in lower-tier packages
- ✓Network Discovery
- ✓Forensic Data Collection
- ✓Guided Onboarding
- ✓Advisory and Training Services
View on vendor site
Core
$5.83/user/mobilled annually$70/yr
Best for: This foundational plan provides essential endpoint protection capabilities
- ✓Cloud-Native NGAV
- ✓Endpoint Protection Platform
- ✓Autonomous Remediation Capabilities
View on vendor site
Control
$6.67/user/mobilled annually$80/yr
Best for: Building on Core, Control adds advanced threat prevention and detection features
- ✓Security Features
- ✓Suite Features
- ✓Includes Purple AI
View on vendor site
MOST POPULARComplete
$15/user/mobilled annually$180/yr
Best for: Complete offers comprehensive EDR and threat hunting functionalities
- ✓AI-Powered First Line of Defense
- ✓Top-tier Endpoint Protection
- ✓Robust EDR (Endpoint Detection and Response) Capabilities
View on vendor site
Commercial
$19/user/mobilled annually$230/yr
Best for: Designed for larger organizations, Commercial includes enterprise-grade features and support
- ✓Foundational AI Security
View on vendor site
Capability Breakdown
5 differences found across 15 standardized features
Feature
Cisco Secure Endpoint
SentinelOne
Network Detection (NDR)
✓
✗
Zero Trust
✓
✗
Firewall
✓
✗
DLP
✓
✗
Deception Technology
✗
✓
Total (raw)
16
16
Cisco Secure Endpoint Features
- •Next-Gen Antivirus
- •EDR (Endpoint Detection & Response)
- •Device Trajectory
- •Orbital Advanced Search
- •SecureX Integration (XDR)
- •Threat Intelligence (Talos)
- •Behavioral Protection
- •Exploit Prevention
- •Malicious Activity Protection
- •Vulnerability Management
- •Quarantine & Remediation
- •iOS Security
- •Meraki Integration
- •Network Security Integration
- •API
- •MITRE ATT&CK
SentinelOne Features
- •AI-Powered Endpoint Protection
- •EDR (Endpoint Detection & Response)
- •XDR (Extended Detection)
- •Autonomous Response (Storyline)
- •Behavioral AI Engine
- •Threat Intelligence
- •Firewall & Device Control
- •Vulnerability Management
- •Cloud Security (Singularity Cloud)
- •Identity Threat Detection (Singularity Identity)
- •Network Discovery (Ranger)
- •Security Data Lake
- •Threat Hunting
- •MITRE ATT&CK Mapping
- •Mobile Protection
- •Multi-Platform
Strengths & Limitations
Evaluative strengths and weaknesses: not feature lists
Pros
- +Leverages Talos intelligence, one of the world's largest threat research teams.
- +Deep integration with Cisco network gear for unparalleled device context.
- +Unified XDR visibility via the included SecureX platform.
- +Orbital advanced search provides deep OS-level visibility using osquery.
- +Strong exploit prevention and behavioral protection against fileless malware.
Cons
- −Lacks native Data Loss Prevention (DLP) and device control features.
- −The user interface can be complex and less intuitive than competitors.
- −Full XDR capabilities require investment in the broader Cisco Secure portfolio.
- −Higher resource consumption (CPU/memory) on endpoints compared to some rivals.
- −Reporting and dashboard customization options are limited.
Pros
- +Autonomous AI response without human intervention
- +Storyline attack correlation simplifies threat hunting
- +Consistently top-performing in MITRE ATT&CK evaluations
- +Unified Singularity XDR across endpoint, cloud, identity
Cons
- −To improve SentinelOne, I would suggest adding a network detection and response capability.
- −There is a clear roadmap for improvements, including enhancing capabilities with AI and seamless functionality in an MSP model for
- −One area for improvement would be the self-healing nature of the agent.
- −To enhance our already strong partnership with SentinelOne, we should focus on improving collaboration.
- −It has a lot of features in place.
At a Glance
User Rating
4.5/5vs4.9/5
Cisco Secure Endpoint
SentinelOne
▲
Starting Price
$6.75/movsContact
Cisco Secure Endpoint
▲
SentinelOne
Feature Count
16 featuresvs16 features
Cisco Secure Endpoint
SentinelOne
User Base
500vs14
Cisco Secure Endpoint
▲
SentinelOne
Cisco Secure Endpoint · Price & Data SyncLast verified: May 30, 2026 · CE-SEC-2026W23-BFBE66 · ✓ Pricing updated May 30, 2026
SentinelOne · Price & Data SyncLast verified: May 30, 2026 · CE-SEC-2026W22-D435BF · ✓ Pricing updated May 30, 2026
Recent Price History
Cisco Secure Endpoint
Cisco Secure Endpoint removed the "Premier" plan
Plan removed · May 30, 2026
Cisco Secure Endpoint
Cisco Secure Endpoint removed the "Advantage" plan
Plan removed · May 30, 2026
Cisco Secure Endpoint
Cisco Secure Endpoint removed the "Essentials" plan
Plan removed · May 30, 2026
Cisco Secure Endpoint
Cisco Secure Endpoint added a new "Secure Endpoint Premier" plan (Custom pricing)
Plan added · May 30, 2026
Cisco Secure Endpoint
Cisco Secure Endpoint added a new "Secure Endpoint Advantage" plan (Custom pricing)
Plan added · May 30, 2026
SentinelOne
SentinelOne added a new "Enterprise" plan (Custom pricing)
Plan added · May 30, 2026
SentinelOne
SentinelOne added a new "Commercial" plan (Custom pricing)
Plan added · May 30, 2026
SentinelOne
SentinelOne updated "Complete" from $13.33/mo to Custom
Price change · May 30, 2026
SentinelOne
SentinelOne updated "Control" from $6.67/mo to Custom
Price change · May 30, 2026
SentinelOne
SentinelOne updated "Core" from $5.83/mo to Custom
Price change · May 30, 2026
Frequently Asked Questions
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